Abstract. Cross-border collaboration is an important part of living lab research, as circumstances and requirements for services and products can vary greatly depending on the region in which they are introduced. While cross-cultural differences can be of interest for these studies, they can also be confounding factors for data collection and analysis. Dissimilarities in the recruitment and in the participation of end users in different regions could influence the outcomes of international studies with multiple implementation sites across countries. Therefore, the current survey study investigates awareness of such cross-cultural differences. The sample consists of 36 living labs from 20 countries. Results show that regional differences are reported in terms of participants’ motivation for participation and the impact of gender, age, professional status, and socio-economic status on participants’ contribution. Additionally, regional differences influence whether a moderator should take the role of a facilitator or a more dominant guide of the process during group sessions. Implementing well-chosen strategies for recruitment, for grouping, and for supporting equal contribution in sessions could improve the quality of international living lab research, while still maintaining sufficient standardisation.